5-meo-dm

5-MeO-DMT is a research chemical psychedelic of the tryptamine class, four to six times more powerful than its better-known cousin, DMT (N, N-dimethyltryptamine). It can be found in a wide variety of trees and shrubs, often alongside DMT and bufotenine (5-HO-DMT), as well as one species of toad. 5-MeO-DMT can also be synthetically produced.

In Central and South America, 5-MeO-DMT is most often sourced from Anadenanthera peregrina (yopo or cohoba) and Virola Theodora—both of which are traditionally harvested to make psychoactive snuff.

It’s also found in the milky white venom of the Sonoran Desert Toad (Bufo alvarius/Incilius alvarius; aka the Colorado River Toad ), which is native to the southwestern United States and northwestern Mexico. Venom harvesting has put pressure on the population of this ecologically sensitive species. It’s currently listed as imperiled or locally instinct in several states in the US. Seeking out alternative sources of 5-MeO DMT, such as synthetic or plant-derived versions, is strongly recommended.

In keeping with its ceremonial use among indigenous Amazonians, 5-MeO-DMT shows great promise in the treatment of certain medical conditions. In fact, a single inhalation of the substance has been shown to greatly improve general well-being and mindfulness as well as reduce the symptoms of psychological disorders.